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. 2022 Mar 11;25(4):104060. doi: 10.1016/j.isci.2022.104060

Figure 5.

Figure 5

Comparison of the effects of polar and hydrophobic mutations on 11CR entry kinetics

(A) The effect of polar mutations on 11CR entry kinetics (mean ± STD).

(B) The effect of hydrophobic substitutions on 11CR entry kinetics (mean ± STD). The A269W mutant only expressed at very low level and failed to regenerate.

(C–E) The Eyring plots of the 11CR entry kinetics (mean ± STD) for the following mutants: F208 A/W, F212 A/W, and F273 A/W. The kinetics were measured using the Alexa 488-based assay.