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. 2022 Feb 1;17:49–70. doi: 10.1016/j.bioactmat.2022.01.038

Table 2.

Summary of studies of polyphenol-based hydrogels for cancer therapy.

Cancer treatment Introduced polyphenols Key properties References
Chemotherapy Dopamine Injectability; Self-healing; Local sustained release [185]
Chemotherapy PDA Adhesion; High drug loading efficiency; Tumor environment-sensitive degradability [188]
Chemotherapy PDA Injectability; pH-sensitive drug release; Biodegradability [189]
Photothermal-mediated therapy PDA Injectability; Self-healing [132]
Photothermal-mediated therapy PDA NIR-sensitive thrombin release [194]
Immunotherapy Dopamine Adhesion; Injectability; Thermosensitivity [196]
Chemo/photothermal therapy Dopamine On-demand drug release [197]