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. 2022 Mar 31;57(1):80–84. doi: 10.5045/br.2021.2021198

Table 1.

Echocardiographic changes after discontinuation of dasatinib.

After HSCT
(total dasatinib use)
Tricuspid Regurgitation (TR) TR velocity Pressure gradient Intravascular septum
0 months (4 mo) Trivial 1.4 m/sec 4 mmHg
20 months (21 mo) Mild 3.4 m/sec 47 mmHg D
Discontinuation of dasatinib
After discontinuation Tricuspid Regurgitation (TR) TR velocity Pressure gradient Intravascular septum
4 days Mild 3.4 m/sec 48.8 mmHg B<C
11 days Trivial 2.7–2.8 m/sec 29.6–31.6 mmHg B<C
1 month Trivial 2.7–2.8 m/sec 31.7 mmHg B<C
3 months Trivial 2.4 m/sec 24.3 mmHg B, mild flat
6 months Trivial 1.5 m/sec No significant pulmonary hypertension Almost normal

Abbreviation: HSCT, hematopoietic stem cell transplantation.