Table 1.
Echocardiographic changes after discontinuation of dasatinib.
| After HSCT (total dasatinib use) |
Tricuspid Regurgitation (TR) | TR velocity | Pressure gradient | Intravascular septum |
|---|---|---|---|---|
| 0 months (4 mo) | Trivial | 1.4 m/sec | 4 mmHg | |
| 20 months (21 mo) | Mild | 3.4 m/sec | 47 mmHg | D |
| Discontinuation of dasatinib | ||||
| After discontinuation | Tricuspid Regurgitation (TR) | TR velocity | Pressure gradient | Intravascular septum |
| 4 days | Mild | 3.4 m/sec | 48.8 mmHg | B<C |
| 11 days | Trivial | 2.7–2.8 m/sec | 29.6–31.6 mmHg | B<C |
| 1 month | Trivial | 2.7–2.8 m/sec | 31.7 mmHg | B<C |
| 3 months | Trivial | 2.4 m/sec | 24.3 mmHg | B, mild flat |
| 6 months | Trivial | 1.5 m/sec | No significant pulmonary hypertension | Almost normal |
Abbreviation: HSCT, hematopoietic stem cell transplantation.