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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Neuropharmacology. 2021 Dec 10;205:108920. doi: 10.1016/j.neuropharm.2021.108920

Figure 2. Direct and indirect effects of insulin receptor deletion in specific populations that reside within or adjacent to the CNS.

Figure 2.

A) Cell type-specific and paracrine effects of IR ablation in neurons, astrocytes, endothelial cells, and myeloid cells. B) Impact of cell type-specific IR deletion on glucoregulation and body weight homeostasis. Abbreviations: HFD, high-fat diet.