TABLE 1.
Cold preservation | Machine perfusion | p-value | |
---|---|---|---|
N = 5,474 | N = 1,136 | ||
Sex, N (%) | 0.660 | ||
Male | 3,388 (61.9) | 711 (62.6) | |
Female | 2,086 (38.1) | 425 (37.4) | |
Age (years), median (IQR) | 34 (24–47) | 36 (26–49) | <0.001 |
Race/ethnicity, N (%) | 0.341 | ||
White | 3,569 (62.5) | 750 (66.0) | |
Black | 849 (15.5) | 169 (14.9) | |
Hispanic | 836 (15.3) | 183 (16.1) | |
Asian/other | 220 (4.0) | 34 (3.0) | |
Hypertension, N (%) | 1,153 (21.2) | 264 (23.5) | 0.091 |
Diabetes, N (%) | 228 (4.2) | 71 (6.3) | 0.002 |
KDPI category, N (%) | 0.003 | ||
<20% | 1,933 (36.5) | 356 (31.4) | |
20–34% | 1,022 (18.7) | 237 (20.9) | |
35–85% | 2,235 (40.9) | 482 (42.5) | |
>85% | 210 (3.9) | 59 (5.2) | |
DCD donor, N (%) | 224 (4.5) | 90 (7.9) | <0.001 |
Kidney CIT (hours), median (IQR) | 10.0 (7.7–12.8) | 12.8 (9.4–21.7) | <0.001 |
Liver CIT (hours), median (IQR) | 6.1 (5.0–7.7) | 6.0 (4.7–7.6) | 0.074 |
Split liver, N (%) | 81 (1.5) | 12 (1.1) | 0.270 |
Distance to donor (miles), median (IQR) | 59 (8–158) | 52 (8–166) | 0.492 |
Share type, N (%) | 0.018 | ||
Local | 4,099 (74.9) | 858 (75.5) | |
Regional | 1,241 (22.7) | 235 (20.7) | |
National | 134 (2.5) | 43 (3.8) | |
Cause of death, N (%) | 0.002 | ||
Anoxia | 1,625 (29.7) | 407 (35.8) | |
Stroke | 1,494 (27.3) | 277 (24.4) | |
Head trauma | 2,188 (40.0) | 420 (37.0) | |
CNS tumor | 35 (0.64) | 5 (0.4) | |
Other | 132 (2.4) | 27 (2.4) | |
BMI (kg/m2), median (IQR) | 25.8 (22.8–29.8) | 26.4 (23.3–30.1) | 0.001 |
Terminal creatinine (mg/dl), median (IQR) | 0.9 (0.7–1.2) | 0.9 (0.7–1.2) | 0.267 |
HCV antibody positive, N (%) | 399 (7.3) | 88 (7.8) | 0.599 |