Table 2:

Hazard ratio, correlation with RGN expression and p-value of recurrence-free survival analysis of indicated genes in three datasets.

	Taylor’s Cohort			Yu’s Cohort			TCGA
Gene Name	Survival	Hazard ratio	Correlation	Survival	Hazard ratio	Correlation	Survival	Hazard ratio	Correlation	No-relapse vs Relapse (Fold Change)	No-relapse vs Relapse (P-value)
	(P-value)	(HR)	(r)	(P-value)	(HR)	(r)	(P-value)	(HR)	(r)
MYL9	***	0.31	0.78	ns	0.48	0.59	*	0.45	0.79	6.74	***
CNN1	***	0.3	0.84	0.08	0.45	0.57	***	0.42	0.8	6.4	**
DES	*	0.5	0.74	*	0.4	0.6	***	0.41	0.78	8.23	***
TPM2	**	0.39	0.78	*	0.36	0.62	***	0.4	0.75	6.36	**
COL4A6	0.08	0.56	0.67	*	0.37	0.55	*	0.5	0.64	4.47	**
KCNMB1	ns	0.52	0.78	ns	0.59	0.65	**	0.5	0.82	4.41	**
ACTG2	*	0.42	0.77	*	0.37	0.55	*	0.41	0.78	8.08	***
WFDC2	*	0.52	0.36	0.07	0.45	0.4	*	0.47	0.45	10.66	****
CSRP1	**	0.36	0.79	0.09	0.46	0.46	*	0.47	0.78	5.79	***
PCP4	*	0.42	0.78	*	0.3	0.46	0.05	0.52	0.69	5.1	**
TGFB1I1	0.06	0.53	0.7	0.17	0.54	0.57	*	0.47	0.7	4.21	**

MYL9: Myosin light chain 9; CNN1: Calponin 1; DES: Desmin; TPM2: Tropomyosin 2; COL4A6: Collagen type IV alpha 6 chain; KCNMB1: Potassium calcium-activated channel subfamily M regulatory beta subunit 1; ACTG2: Actin gamma 2, smooth muscle; WFDC2: WAP four disulfide core domain 2; CSRP1: Cysteine and glycine rich protein 1; PCP4: Purkinje cell protein 4; TGFB1I1: Transforming growth factor beta 1 induced transcript 1.