Fig. 6.

BRCA samples miR-205 expression distribution in healthy (blue) and tumoral (orange) samples (a); BRCA patients have been split into two groups based on ZEB1, ZEB2, miR-205-5p median (respectively in b, c, d). The blue line represents the group with higher expression of the analyzed feature while the orange line represents the group associated with lower expression. No significant association between expression and overall survival have been found using ZEB1, ZEB2, miR-205-5p individually (Kaplan-Meier log rank p > 0.05). The BRCA population has been split using both miR-205/ZEB1 and miR-205/ZEB2 expressions (e, f respectively). In both cases miRNA overexpression and gene under expression appears to be significantly associated with low survival rate (orange line, p-value < 0.05).