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. 2022 Jan 25;16:149–161. doi: 10.1016/j.bioactmat.2022.01.031

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© 2022 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 5 — Evaluation of tendon regeneration. (A) Immunohistochemical staining of collagen I; (B–D) tendon-related gene expression of regenerative tissue at 1 and 3 M; (E) representative TEM images and distribution of regenerative tendon tissue. Significant difference compared with the defect (*), autograft (⁺), and NS (^#) groups, P < 0.05; Significant difference compared with the NS (**), CNS1 (⁺⁺), and CNS2 (^##) groups, P < 0.01; 1 M, 1 month; 3 M, 3 months; CNS, crimped nanofiber scaffold; NS, nanofiber scaffold; TEM, transmission electron microscopy; Tnmd, tenomodulin.