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. 2022 Mar 3;60:101468. doi: 10.1016/j.molmet.2022.101468

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This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Supplemental Figure 8 — Reduction of G6PDH abundance protects against the motor neuron toxicity of PR50 and GA50. Panel A. A three-way comparison of number of motor neurons expressing LacZ + scr, PR50 + scr miRNA and PR50 + G6PDH miRNA. Statistically significant group differences were seen by ANOVA and post hoc test reveal that PR50 + scr miRNA is significant different from LacZ + scr and from PR50 + G6PDH miRNA. Results from ≥4 experiments, ∗, p < 0.05. A three-way comparison of number of motor neurons expressing LacZ + scr, GA50 + scr miRNA and GA50 + G6PDH miRNA. Statistically significant group differences were seen by ANOVA and post hoc test reveal that GA50 + scr miRNA is significant different from LacZ + scr and from GA50 + G6PDH miRNA. Results from ≥4 experiments, ∗, p < 0.05.