Table 2.
Glomerulonephritis associated with chronic infection in patients on long-term parenteral nutrition
| References | Patient (sex, age] | Underlying disease | TPN, years | Blood culture | PR3-ANCA, U/mL | Renal biopsy | Treatment | Outcome recovery |
|---|---|---|---|---|---|---|---|---|
| Yared et al. [3] | M, 66 | SBS | 5 | S. epidermidis, C. jeikeium | N/D | MPGN | ATB, CVC removal | Full |
| F, 45 | SBS | 3 | Unknown | N/D | MPGN | ATB, CVC removal | Full | |
| Ohara et al. [4] | M, 13 | SBS | 13 | S. epidermidis | N/D | MPGN IF: C3, IgM, Cl |
ATB, CVC removal | Full |
| Kusaba et al. [5] | F, 59 | Post-radiation enteritis | 2 | S. epidermidis | Negative | Crescentic GN* IF: C3, IgM, IgG |
ATB, CVC removal | ESRD |
| Sy et al. [6] | M, 23 | SBS | ||||||
| 1st episode | 6 | S. epidermidis | N/D | MPGN IF: IgM, C3 | ATB, CVC removal | Full | ||
| 2nd episode | 19.5 | S. epidermidis | Negative | MPGN | ATB, CVC removal | Partial | ||
| 3rd episode | 20 | S. epidermidis | N/D | No | ATB, CVC removal | Partial | ||
| Hayashi et al. [7] | F, 45 | Eating disorder | 1.5 | MRCNS | Negative | MPGN | ATB, CVC removal | Partial |
| Okada et al. [8] | M, 12 | MMIHS | 8 | S. epidermidis | Positive 33 | MPGN IF: C3, IgM, C1q |
Pred, mizoribine, ATB, CVC removal | Full |
| F, 24 | MMIHS | 18 | MRSE | Positive 19 | MPGN IF: C3, IgM |
ATB, CVC removal, MP, pred | Full | |
| Current case report | F, 16 | SBS | 11 | E. faecalis, S. hominis | Positive 17 | Crescentic GN** IF: Negative |
ATB, CVC removal, MP, pred, RTX | Full |
TPN, total parenteral nutrition; M, male; F, female; SBS, short bowel syndrome; S. epidermidis, Staphylococcus epidermidis; C. jeikeium, Corynebacterium jeikeium; MRCNS, methicillin-resistant coagulase-negative staphylococci; MRSE, methicillin-resistant Staphylococcus epidermidis; E. faecalis, Enterococcus faecalis; S. hominis, Staphylococcus hominis; N/D, no data; MPGN, membranoproliferative glomerulonephritis; ATB, antibiotics; CVC, central venous catheter; IF, immunofluorescence; ESRD, end stage renal disease; MMIHS, megacystis microcolon intestinal hypoperistalsis syndrome; pred, prednisolone; MP, methylprednisolone; RTX, rituximab.
Crescentic glomerulonephritis induced by catheter-related bloodstream infection (ANCA-negative].
Crescentic ANCA-associated glomerulonephritis.