Table 1.
Genes examined using the NCC Oncopanel test
| Mutations and copy number alterations for all exons | Fusions | ||||
|---|---|---|---|---|---|
| ABL1 | CRKL | IDH2 | NF1 | RAC2 | ALK |
| ACTN4 | CREBBP | IGF1R | NFE2L2/Nrf2 | RAD51C | AKT2 |
| AKT1 | CTNNB1 | IGF2 | NOTCH1 | RAF1/CRAF | BRAF |
| AKT2 | CUL3 | IL7R | NOTCH2 | RB1 | ERBB4 |
| AKT3 | DDR2 | JAK1 | NOTCH3 | RET | FGFR2 |
| ALK | EGFR | JAK2 | NRAS | RHOA | FGFR3 |
| APC | ENO1 | JAK3 | NRG1 | ROS1 | NRG1 |
| ARAF | EP300 | KDM6A/UTX | NTRK1 | SETBP1 | NTRK1 |
| ARID1A | ERBB2/HER2 | KEAP1 | NTRK2 | SETD2 | NTRK2 |
| ARID2 | ERBB3 | KIT | NTRK3 | SMAD4 | PDGFRA |
| ATM | ERBB4 | KRAS | NT5C2 | SMARCA4/BRG1 | RET |
| AXIN1 | ESR1/ER | MAP2K1/MEK1 | PALB2 | SMARCB1 | ROS1 |
| AXL | EZH2 | MAP2K2/MEK2 | PBRM1 | SMO | |
| BAP1 | FBXW7 | MAP2K4 | PDGFRA | STAT3 | |
| BARD1 | FGFR1 | MAP3K1 | PDGFRB | STK11/LKB1 | |
| BCL2L11/BIM | FGFR2 | MAP3K4 | PIK3CA | TP53 | |
| BRAF | FGFR3 | MDM2 | PIK3R1 | TSC1 | |
| BRCA1 | FGFR4 | MDM4 | PIK3R2 | VHL | |
| BRCA2 | FLT3 | MET | POLD1 | ||
| CCND1 | GNA11 | MLH1 | POLE | ||
| CD274/PD-L1 | GNAQ | MTOR | PRKCl | ||
| CDK4 | GNAS | MSH2 | PTCH1 | ||
| CDKN2A | HRAS | MYC | PTEN | ||
| CHEK2 | IDH1 | MYCN | RAC1 | ||