Arendt 1988.

Methods	Double‐blind cross‐over study
Participants	52 of 61 participants flying from the UK to Australia & New Zealand and back completed the crossover.
Interventions	Melatonin 5mg or placebo. For eastward flights this was taken for 2 days before the flight at the local time, which corresponded to 2am at the destination time zone, and for 4 days after arrival at the local bedtime ['pre+post']. For westward flights melatonin or placebo was taken at the local bedtime for 4 days after arrival
Outcomes	Self‐rated jet lag (VAS), symptoms
Notes	This study is briefly reported by Skene 1989 in congress proceedings
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear