FIG. 2.

Effects in mice of treatment with a single oral dose (400 mg/kg) of pefloxacin on the incorporation of simultaneously administered ³⁵S in vivo in blood (log plot) (A) and FHCs (B). Controls received the same volume of saline solution instead of pefloxacin. Values for ³⁵S incorporation are means ± SEM of results from four experiments. ∗, P < 0.05; ∗∗, P < 0.01 versus controls, by Student’s t test.