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. 2022 Jan 12;6(1):BJGPO.2021.0208. doi: 10.3399/BJGPO.2021.0208

Table 3. Multivariate logistic model on associations between NSAID prescription and AKI within 4 months from the start of prescription period.

Characteristic Odds ratio 95% CI P-value
Age group, years (versus 18–40) 40–59 1.65 1.27 2.18 <0.001
60–79 3.98 3.07 5.22 <0.001
≥80 7.57 5.53 10.42 <0.001
Sex (versus male) Female 1.11 0.97 1.27 0.13
Socioeconomic status, IMD quintile (versus 5, least deprived) 4 1.19 0.96 1.46 0.11
3 1.29 1.04 1.59 0.02
2 1.64 1.34 2.01 <0.001
1 (most deprived) 1.69 1.36 2.09 <0.001
CKD (versus no CKD) 1.61 1.30 1.97 <0.001
CVD (versus no CVD) 1.78 1.47 2.14 <0.001
Heart failure (versus no heart failure) 1.78 1.23 2.51 0.001
Diabetes (type 1 or 2 versus no diabetes) 1.50 1.25 1.78 <0.001
Hypertension (versus no hypertension) 1.41 1.21 1.64 <0.001

Cohort: N = 77 422; AKI: n = 915. CKD = chronic kidney disease. CVD = cardiovascular disease. IMD = Index of Multiple Deprivation.