Table 1.
Clinical and demographic characteristics of overall study group and stratified by procalcitonin of 0.25 ng/mL and 0.50 ng/ml.
| Procalcitonin |
|||||||||
|---|---|---|---|---|---|---|---|---|---|
| Overall (N = 223) |
< 0.25 ng/mL (n = 148) |
≥ 0.25 ng/mL (n = 75) |
p | < 0.50 ng/mL (n = 187) |
≥ 0.50 ng/mL (n = 36) |
p | |||
| Age (Years) | 63 [52-75] | 63 [52-75] | 62 [47-75] | 0.651 | 63 [52-75] | 62 [46-76] | 0.647 | ||
| Biological Sex | |||||||||
| Female | 116 (52.5) | 77 (52.7) | 39 (52.0) | 0.917 | 96 (51.9) | 20 (55.6) | 0.687 | ||
| Male | 105 (47.5) | 69 (47.3) | 36 (48.0) | 89 (48.1) | 16 (44.4) | ||||
| Race/Ethnicity | |||||||||
| White | 107 (48.9) | 80 (54.8) | 27 (37.0) | 0.053 | 93 (50.5) | 14 (40.0) | 0.100 | ||
| Black | 28 (12.8) | 15 (10.3) | 13 (17.8) | 24 (13.1) | 4 (11.4) | ||||
| Hispanic | 68 (31.1) | 43 (29.5) | 25 (34.3) | 57 (31.0) | 11 (31.4) | ||||
| Asian | 16 (7.3) | 8 (5.5) | 8 (11.0) | 10 (5.4) | 6 (17.2) | ||||
| Obesity | 153 (69.6) | 101 (69.2) | 52 (70.3) | 0.868 | 132 (71.4) | 21 (60.0) | 0.181 | ||
| CAD | 49 (22.2) | 34 (23.0) | 15 (20.6) | 0.683 | 43 (23.0) | 6 (17.7) | 0.490 | ||
| CKD | 29 (13.0) | 13 (8.8) | 16 (21.3) | 0.009 | 24 (12.8) | 5 (13.9) | 0.863 | ||
| Cancer | 17 (7.6) | 10 (6.8) | 7 (9.3) | 0.493 | 13 (7.0) | 4 (11.1) | 0.389 | ||
| COPD | 24 (11.0) | 16 (11.0) | 8 (11.0) | 1.000 | 17 (9.2) | 7 (20.0) | 0.076 | ||
| Asthma | 17 (7.8) | 12 (8.3) | 5 (6.9) | 0.711 | 14 (7.7) | 3 (8.6) | 0.741 | ||
| Diabetes | 110 (50.2) | 78 (53.4) | 32 (43.8) | 0.181 | 94 (51.1) | 16 (45.7) | 0.560 | ||
| APACHE II | 8 [6-12] | 8 [6-12] | 9 [6-14] | 0.042 | 8 (6-12) | 11 (6-15) | 0.088 | ||
| CRP (μg/mL) | 86 [44-453] | 79 [41-133] | 111 [61-186] | 0.007 | 82 [41-142] | 131 [68-223] | 0.010 | ||
| Maximum Ferritin (μg/L) | 606 [344-1216] | 595 [344-1111] | 628 [316-1328] | 0.741 | 595 [344-1216] | 628 [279-1328] | 0.629 | ||
| LDH (U/L) | 337 [276-460] | 327 [278-440] | 369 [276-517] | 0.077 | 331 [276-454] | 369 [264-461] | 0.386 | ||
| In-hospital death | 31 (14.6) | 18 (12.9) | 13 (18.1) | 0.310 | 25 (14.1) | 6 (17.1) | 0.644 | ||
| Hospital Stay (Days) | 10 [8-13] | 10 [8-14] | 11 [7-14] | 0.144 | 10 [8-13] | 13 [7-16] | 0.368 | ||
| ICU Stay | |||||||||
| No | 114 (53.8) | 82 (58.6) | 32 (44.4) | 0.051 | 100 (56.5) | 14 (40.0) | 0.074 | ||
| Yes | 98 (46.2) | 58 (41.4) | 40 (55.6) | 77 (43.5) | 21 (60.0) | ||||
| ICU Days | 10 [7-13] | 10 [7-14] | 12 [5-15] | 0.986 | 10 [7-14] | 9 [3-13] | 0.218 | ||
| Intubation | |||||||||
| No | 136 (63.9) | 92 (65.3) | 44 (61.1) | 0.552 | 116 (65.2) | 20 (57.1) | 0.366 | ||
| Yes | 77 (36.2) | 49 (34.8) | 28 (38.9) | 62 (34.8) | 15 (42.9) | ||||
| Intubation Days | 13 [10-16] | 13 [8-16] | 13 [10-25] | 0.552 | 14 [8-17] | 13 [7-20] | 0.768 | ||
Note. Data presented as median [IQR] or n (%). For length of stay and length of intubation, data are presented as median [95% CI] based on Kaplan-Meier estimates that accounted for censoring due to in-hospital death.