Table 1.

Dose constraints for organs at risk depending on fractionation

Organ at risk	Dose constraints (Gy)
Number of fractions	3 Fractions	5 Fractions	6 Fractions	8 Fractions	10 Fractions
Uninvolved liver (= liver-CTV) ≥ 700 cm3	< 19.2	< 24	< 26	< 29	< 32
Stomach D0.5cm3	< 22.2	< 35	< 37	< 40	< 43.5
Duodenum D0.5cm3	< 22.2	< 35	< 37	< 40	< 43.5
Bowel D0.5cm3	< 25.2	< 35	< 37	< 40	< 43.5
Sigma/Rectum D0.5cm3	< 28.2	< 34	< 37	< 41	< 44.0
Esophagus D0.5cm3	< 25.2	< 34	< 36	< 40	< 43.5
Heart D0.5cm3	< 25.0	< 29.0	< 31.5	< 60.0	< 66.0
Kidneys Mean dose	< 8.5	< 10.0	< 10.8	< 11.5	< 12.0
Spinal cord D0.1cm3	< 21.6	< 27.0	< 29.0	< 32.0	< 35.0

CTV, clinical target volume; D_xcm3, dose which is received by less than × cm³