Table 2.
Change in Linear Growth Between Enrollment and Follow-up in Children From 7 Global Enteric Multicenter Study Sites, by Age Group, Using Individual- and Multiple-Pathogen Models
| Individual-Pathogen Model | Multiple-Pathogen Model | ||||
|---|---|---|---|---|---|
| Pathogen by Age Group | Episodes With pathogen, No. (%) | Difference in ΔHAZ (95% CI) | P Value | Difference in ΔHAZ (95% CI) | P Value |
| Age 0–11 mo (n = 3408) | |||||
| Cryptosporidium | 525 (15.4) | −0.09 (−.14 to −.04) | <.001 | −0.09 (−.14 to −.04) | <.001 |
| Shigella, not treated with antibiotic | 72 (2.1) | −0.16 (−.29 to −.03) | .02 | −0.17 (−.31 to −.04) | .009 |
| Shigella, treated with antibiotic | 93 (2.7) | 0.05 (−.07 to .17) | .38 | 0.05 (−.07 to .17) | .41 |
| Typical EPEC | 304 (8.9) | −0.08 (−.15 to −.02) | .01 | −0.08 (−.15 to −.02) | .01 |
| Rotavirus | 859 (25.2) | 0.02 (−.02 to .06) | .40 | … | … |
| ST-ETEC | 203 (6.0) | 0.006 (−.07 to .08) | .89 | … | … |
| Adenovirus 40/41 | 104 (3.0) | −0.06 (−.17 to .05) | .27 | … | … |
| Age 12–23 mo (n = 2741) | |||||
| Cryptosporidium | 312 (11.4) | −0.05 (−.09 to −.003) | .04 | −0.05 (−.09 to −.005) | .03 |
| Shigella, not treated with antibiotic | 159 (5.8) | −0.06 (−.12 to .006) | .08 | −0.06 (−.12 to .001) | .054 |
| Shigella, treated with antibiotic | 282 (10.3) | 0.07 (0.01 to 0.13) | .02 | 0.06 (.009 to .13) | .02 |
| Rotavirus | 492 (18.0) | −0.04 (−.07 to .002) | .06 | … | … |
| ST-ETEC | 199 (7.3) | −0.12 (−.17 to −.06) | <.001 | −0.12 (−.17 to −.06) | <.001 |
| Adenovirus 40/41 | 76 (2.8) | 0.008 (−.08 to .09) | .86 | … | … |
Abbreviations: ΔHAZ, change in height-for-age z scores; CI, confidence interval; ST-ETEC, enterotoxigenic Escherichia coli encoding heat-stable toxin.