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. Author manuscript; available in PMC: 2022 Mar 28.
Published in final edited form as: Nat Biomed Eng. 2021 Sep 13;5(9):1099–1109. doi: 10.1038/s41551-021-00793-y

Fig. 2 |. Nanostructures of the self-assembled MP pairs.

Fig. 2 |

a, Schematic of TTX binding to MPs approximated by self-assembly into nanostructures. b, MPs with different hydrophobic domains. red, P1; blue, P2. c, TEM images of different pairs of MPs. In each pair, the molar ratio of MP1:MP2 was 1:1 and the concentration was 62.6 μM. d, TTX release from each formulation over 12 h. In each group, the ratio of MP1:MP2:TTX was 1:1:1 and their concentration was 62.6 μM. The release over 48 h is shown in Supplementary Fig. 6. Data are shown as the mean ± s.d. (n = 4). ϕFFF-P1P2 + TTX and ϕYFY-P1P2 + TTX groups versus free TTX group, P < 0.0001. e, CD spectrum of each MP pair. All the peptide solutions have the same concentration (20 μM).