FIGURE 2.
Pretreatment with RS-09 protects mice from S. Typhimurium infection. (A) Survival rates of mice following RS-09 pretreatment and challenge with pathogenic S. Typhimurium. RS-09 was administered to mice for 7 days, and they were then orally injected with a sublethal dose of Sty14028 suspension (105 CFU/mouse). The survival of mice was recorded daily. (B) Comparison of body weight loss (current body weight/original body weight before infection) over 8 days post-infection daily. (C) RS-09 relieved Sty14028-induced splenomegaly (the scale is shown in the diagram). (D) The liver weight index (liver weight/body weight) (E) The splenic weight index (spleen weight/body weight). Data are the means ± SD (n = 6). *p < 0.05.