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. 2022 Mar 8;9:783618. doi: 10.3389/fmed.2022.783618

Table 2.

Adjusted hazard ratio (95% confidence interval) of all-cause mortality.

Model 1 p for trend Model 2 p for trend Model 3 p for trend Model 4 p for trend
LDL-C <0.001 <0.001 <0.001 0.011
<2.61 mmol/L 1.70 (1.28–2.25)* 1.67 (1.26–2.21)* 1.57 (1.17–2.11)* 1.46 (1.07–2.00)*
2.61–3.09 mmol/L 1.30 (0.97–1.75) 1.28 (0.95–1.73) 1.20 (0.88–1.64) 1.17 (0.84–1.62)
3.10–3.50 mmol/L 1.20 (0.89–1.61) 1.14 (0.85–1.54) 1.18 (0.87–1.61) 1.12 (0.81–1.55)
3.51–4.09 mmol/L 1.05 (0.77–1.43) 1.02 (0.75–1.39) 0.96 (0.69–1.33) 0.95 (0.67–1.35)
≥4.10 mmol/L 1 1 1 1
HDL-C 0.732 0.878 0.494 0.426
<1.09 mmol/L 1.48 (1.11–1.98)* 1.46 (1.09–1.95)* 1.57 (1.15–2.15)* 1.55 (1.11–2.16)*
1.09–1.20 mmol/L 1.04 (0.77–1.41) 1.05 (0.77–1.42) 1.11 (0.81–1.54) 1.19 (0.84–1.67)
1.21–1.39 mmol/L 1 1 1 1
1.40–1.60 mmol/L 1.20 (0.89–1.61) 1.21 (0.89–1.63) 1.27 (0.92–1.74) 1.37 (0.98–1.92)
≥1.61 mmol/L 1.41 (1.05–1.91)* 1.45 (1.07–1.96)* 1.45 (1.04–2.01)* 1.42 (1.00–2.02)*

Model 1 adjusted for age, sex, educational years, low family income, cigarette smoking, alcohol drinking, tea-drinking, physical activity, and obesity.

Model 2 further adjusted for hypertension, type II diabetes, stroke, heart diseases, cancer, and depression.

Model 3 excluded those who died within 2 years of initial cholesterol measurement (n = 60) on the basis of model 2.

Model 4 excluded those who were functionally impaired (n = 212) on the basis of model 2.

LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol.

*

p < 0.05.