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Approved/investigational drugs targeting hub common susceptibility genes.
| Drug | Target gene | Effect |
|---|---|---|
| Glatiramer acetate | HLA-DRB1 | Immunomodulator |
| Daclizumab | IL2RA | Anti-CD25(IL-2) antibody |
| Filgotinib | JAK1, TYK2 | JAK inhibitor |
| Tofacitinib | JAK1, TYK2 | JAK inhibitor |
