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. 2022 Mar 9;4:794908. doi: 10.3389/fdgth.2022.794908

Table 5.

Use of connected devices and social media enabled features in clinical research by age class.

Total 18–24 years 25–34 years 35–44 years 45–54 years 55–64 years 65 years or over Global p-value
A B C D E F
Would you be willing to use a health-related connected object within the context of a clinical study?
N = 1529 N = 102 N = 337 N = 350 N = 306 N = 265 N = 169
No 95 (6.2%) 2 (2.0%) 9 (2.7%) 10 (2.9%) 18 (5.9%) 30 (11.3%) 26 (15.4%) <0.001
Yes 1434 (93.8%) 100 (98.0%) 328 (97.3%) 340 (97.1%) 288 (94.1%) 235 (88.7%) 143 (84.6%)
Significant difference with other age class E F E F E F F A B C A B C D
If yes, please specify which one(s)
N = 1434 N = 100 N = 328 N = 340 N = 288 N = 235 N = 143
Connected weighing scales 1312 (91.5%) 92 (92.0%) 317 (96.6%) 319 (93.8%) 263 (91.3%) 204 (86.8%) 117 (81.8%) <0.001
Significant difference with other age class D E F E F B F B C B C D
Connected watch/wristband 1306 (91.1%) 94 (94.0%) 311 (94.8%) 323 (95.0%) 262 (91.0%) 208 (88.5%) 108 (75.5%) <0.001
Significant difference with other age class F F E F F C F A B C D E
Connected patch 1,032 (72.0%) 77 (77.0%) 275 (83.8%) 254 (74.7%) 201 (69.8%) 147 (62.6%) 78 (54.5%) <0.001
Significant difference with other age class F C D E F B E F B F B C A B C D
Connected plate 1001 (69.8%) 79 (79.0%) 260 (79.3%) 251 (73.8%) 199 (69.1%) 141 (60.0%) 71 (49.7%) <0.001
Significant difference with other age class E F D E F E F B F A B C A B C D
Connected glasses 789 (55.0%) 64 (64.0%) 219 (66.8%) 200 (58.8%) 154 (53.5%) 107 (45.5%) 45 (31.5%) <0.001
Significant difference with other age class E F D E F E F B F A B C F A B C D E
What concerns you about the use of connected objects in clinical research?
N = 1529 N = 102 N = 337 N = 350 N = 306 N = 265 N = 169
Protection of your personal data 574 (37.5%) 22 (21.6%) 109 (32.3%) 137 (39.1%) 128 (41.8%) 106 (40.0%) 72 (42.6%) 0.001
Significant difference with other age class C D E F - A A A A
Concerns that the tool will be unreliable 543 (35.5%) 54 (52.9%) 147 (43.6%) 137 (39.1%) 96 (31.4%) 77 (29.1%) 32 (18.9%) <0.001
Significant difference with other age class D E F D E F F A B F A B A B C D
Concerns about not being able to use the object 436 (28.5%) 20 (19.6%) 75 (22.3%) 88 (25.1%) 89 (29.1%) 91 (34.3%) 73 (43.2%) <0.001
Significant difference with other age class F E F F F B A B C D
Loss of human interaction 371 (24.3%) 26 (25.5%) 70 (20.8%) 66 (18.9%) 73 (23.9%) 77 (29.1%) 59 (34.9%) <0.001
Significant difference with other age class F E F C B C
Ease of use 323 (21.1%) 20 (19.6%) 86 (25.5%) 87 (24.9%) 57 (18.6%) 51 (19.2%) 22 (13.0%) 0.009
Significant difference with other age class F F B C
Location tracking 285 (18.6%) 17 (16.7%) 54 (16.0%) 74 (21.1%) 57 (18.6%) 60 (22.6%) 23 (13.6%) 0.115
Significant difference with other age class
Impact on understanding 234 (15.3%) 18 (17.6%) 46 (13.6%) 51 (14.6%) 47 (15.4%) 43 (16.2%) 29 (17.2%) 0.861
Significant difference with other age class
Concerns of less efficient monitoring 173 (11.3%) 18 (17.6%) 37 (11.0%) 33 (9.4%) 42 (13.7%) 25 (9.4%) 18 (10.7%) 0.149
Significant difference with other age class
Reluctance from healthcare professionals 124 (8.1%) 12 (11.8%) 30 (8.9%) 24 (6.9%) 22 (7.2%) 25 (9.4%) 11 (6.5%) 0.493
Significant difference with other age class
In your opinion, what would be the best study format for conducting clinical studies?
N = 1529 N = 102 N = 337 N = 350 N = 306 N = 265 N = 169
Digital 276 (18.1%) 14 (13.7%) 51 (15.1%) 79 (22.6%) 60 (19.6%) 38 (14.3%) 34 (20.1%) <0.001
Exclusively physical 212 (13.9%) 9 (8.8%) 31 (9.2%) 26 (7.4%) 38 (12.4%) 57 (21.5%) 51 (30.2%)
Digital and physical 1041 (68.1%) 79 (77.5%) 255 (75.7%) 245 (70.0%) 208 (68.0%) 170 (64.2%) 84 (49.7%)
Significant difference with other age class F E F E F F B C A B C D
What would be the best way to provide information regarding a clinical research protocol?
N = 1529 N = 102 N = 337 N = 350 N = 306 N = 265 N = 169
Paper document with explanations from a professional 383 (25.0%) 17 (16.7%) 68 (20.2%) 64 (18.3%) 75 (24.5%) 85 (32.1%) 74 (43.8%) <0.001
Video and discussion with a professional and/or a quiz on key points 378 (24.7%) 36 (35.3%) 78 (23.1%) 89 (25.4%) 77 (25.2%) 65 (24.5%) 33 (19.5%)
A fun mobile app 768 (50.2%) 49 (48.0%) 191 (56.7%) 197 (56.3%) 154 (50.3%) 115 (43.4%) 62 (36.7%)
Significant difference with other age class F E F E F F B C A B C D
If you had to provide health-related data within the context of a clinical study, what would you consider the most appropriate format?
N = 1529 N = 102 N = 337 N = 350 N = 306 N = 265 N = 169
Paper questionnaire 104 (6.8%) 12 (11.8%) 20 (5.9%) 19 (5.4%) 15 (4.9%) 22 (8.3%) 16 (9.5%) <0.001
Questionnaire on a mobile app 982 (64.2%) 74 (72.5%) 271 (80.4%) 268 (76.6%) 183 (59.8%) 132 (49.8%) 54 (32.0%)
Questionnaire on a PC 443 (29.0%) 16 (15.7%) 46 (13.6%) 63 (18.0%) 108 (35.3%) 111 (41.9%) 99 (58.6%)
Significant difference with other age class D E F D E F D E F A B C F A B C F A B C D E
Would you agree to share, in a secure and anonymous manner, your social media content (Facebook, Twitter, Instagram, etc.) with research staff?
N = 1529 N = 102 N = 337 N = 350 N = 306 N = 265 N = 169
No 606 (39.6%) 33 (32.4%) 115 (34.1%) 128 (36.6%) 118 (38.6%) 123 (46.4%) 89 (52.7%) <0.001
Yes 923 (60.4%) 69 (67.6%) 222 (65.9%) 222 (63.4%) 188 (61.4%) 142 (53.6%) 80 (47.3%)
Significant difference with other age class F E F F F B A B C D
Would you be prepared to interact with an online chat system (chatbot) and send your recorded health information to a member of the research team?
N = 1529 N = 102 N = 337 N = 350 N = 306 N = 265 N = 169
No 272 (17.8%) 18 (17.6%) 38 (11.3%) 47 (13.4%) 43 (14.1%) 64 (24.2%) 62 (36.7%) <0.001
Yes 1257 (82.2%) 84 (82.4%) 299 (88.7%) 303 (86.6%) 263 (85.9%) 201 (75.8%) 107 (63.3%)
Significant difference with other age class F E F E F E F B C D F A B C D E

Global p-value, when significant; Age classes, Significant difference with other age classes; N = number of participants per age class.