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. 2022 Mar 9;10:843671. doi: 10.3389/fcell.2022.843671

TABLE 1.

JAMs in germ cell motility, polarization, and maturation.

Protein Location Partner Final effect
JAM-A Sertoli cell and a subset of basal GCs P-glycoprotein Maintains the BTB integrity
Su et al. (2009)
CASK
Aravindan et al. (2012)
JAM-B BTB between Sertoli and germ cells JAM-C on spermatids Promotes germ cells to transit across the BTB
Ebnet (2017) Wang and Lui (2009)
JAM-C Germ/Sertoli cell Par6/Pals Mediates spermatid polarization and differentiation and produces mature sperm cells
Wong et al. (2008)
Par-3
Fujita et al. (2007)
CAR
Sultana et al. (2014)