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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Acc Chem Res. 2021 Dec 29;55(3):373–380. doi: 10.1021/acs.accounts.1c00632

Figure 5.

Figure 5.

Structure of wild-type (2CPP) and the D251E P450cam mutant (6WE6). The mutant side chain is close enough to Asp182 for H-bonding interactions. The corresponding residue in CYP101D1 is Asn.