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. 2022 Mar 9;12:752176. doi: 10.3389/fendo.2021.752176

Table 3.

Demographic and clinicopathological characteristics in pancreatic cancer patients with bone metastasis.

Characteristics Training cohort (N=167) Validation cohort (N=68) χ2 P
n % n %
Age 63.27±12.195 66.41±11.820 0.072*
Race 0.220 0.896
 White 135 80.84 54 79.41
 Black 18 10.78 7 10.29
 Other 14 8.38 7 10.29
Sex 2.193 0.139
 Female 74 44.31 23 33.82
 Male 93 55.69 45 66.18
Histological subtype 0.998 0.802
 Adenocarcinoma 108 64.67 43 63.24
 Infiltrating duct carcinoma 13 7.78 8 11.76
 Neuroendocrine carcinoma 21 12.57 8 11.76
 Other 25 14.97 9 13.24
Grade 1.386 0.709
 Well differentiated: I 20 11.98 7 10.29
 Moderately differentiated: II 58 34.73 29 42.65
 Poorly differentiated: III 77 46.11 27 39.71
 Undifferentiated; anaplastic: IV 12 7.19 5 7.35
Primary Site 3.489 0.745
 Head of pancreas 49 29.34 25 36.76
 Body of pancreas 28 16.77 8 11.76
 Tail of pancreas 53 31.74 18 26.47
 Pancreatic duct 1 0.60 1 1.47
 Other specified parts of pancreas 6 3.59 2 2.94
 Overlapping lesion of pancreas 19 11.38 7 10.29
 Pancreas, NOS 11 6.59 7 10.29
AJCC T stage 0.325 0.955
 T1 7 4.19 3 4.41
 T2 53 31.74 22 32.35
 T3 65 38.92 24 35.29
 T4 42 25.15 19 27.94
AJCC N stage 1.129 0.288
 N0 66 39.52 32 47.06
 N1 101 60.48 36 52.94
Surgery 0.625 0.429
 No 152 91.02 64 94.11
 Yes 15 8.98 4 5.88
Radiotherapy 0.283 0.595
 No 117 70.06 50 73.53
 Yes 50 29.94 18 26.47
Chemotherapy 0.157 0.692
 No 71 42.51 27 39.71
 Yes 96 57.49 41 60.29
Tumor size 2.186 0.335
 4-38 mm 63 37.72 29 42.65
 39-67 mm 74 44.31 32 47.06
 68-150 mm 30 17.96 7 10.29
Brain metastasis 0.079 0.779
 No 159 95.21 66 97.06
 Yes 8 4.79 2 2.94
Liver metastasis 0.975 0.323
 No 55 32.93 27 39.71
 Yes 112 67.07 41 60.29
Lung metastasis 0.975 0.323
 No 112 67.07 41 60.29
 Yes 55 32.93 27 39.71

*T test.