Table 3.
Demographic and clinicopathological characteristics in pancreatic cancer patients with bone metastasis.
| Characteristics | Training cohort (N=167) | Validation cohort (N=68) | χ2 | P | ||
|---|---|---|---|---|---|---|
| n | % | n | % | |||
| Age | 63.27±12.195 | 66.41±11.820 | 0.072* | |||
| Race | 0.220 | 0.896 | ||||
| White | 135 | 80.84 | 54 | 79.41 | ||
| Black | 18 | 10.78 | 7 | 10.29 | ||
| Other | 14 | 8.38 | 7 | 10.29 | ||
| Sex | 2.193 | 0.139 | ||||
| Female | 74 | 44.31 | 23 | 33.82 | ||
| Male | 93 | 55.69 | 45 | 66.18 | ||
| Histological subtype | 0.998 | 0.802 | ||||
| Adenocarcinoma | 108 | 64.67 | 43 | 63.24 | ||
| Infiltrating duct carcinoma | 13 | 7.78 | 8 | 11.76 | ||
| Neuroendocrine carcinoma | 21 | 12.57 | 8 | 11.76 | ||
| Other | 25 | 14.97 | 9 | 13.24 | ||
| Grade | 1.386 | 0.709 | ||||
| Well differentiated: I | 20 | 11.98 | 7 | 10.29 | ||
| Moderately differentiated: II | 58 | 34.73 | 29 | 42.65 | ||
| Poorly differentiated: III | 77 | 46.11 | 27 | 39.71 | ||
| Undifferentiated; anaplastic: IV | 12 | 7.19 | 5 | 7.35 | ||
| Primary Site | 3.489 | 0.745 | ||||
| Head of pancreas | 49 | 29.34 | 25 | 36.76 | ||
| Body of pancreas | 28 | 16.77 | 8 | 11.76 | ||
| Tail of pancreas | 53 | 31.74 | 18 | 26.47 | ||
| Pancreatic duct | 1 | 0.60 | 1 | 1.47 | ||
| Other specified parts of pancreas | 6 | 3.59 | 2 | 2.94 | ||
| Overlapping lesion of pancreas | 19 | 11.38 | 7 | 10.29 | ||
| Pancreas, NOS | 11 | 6.59 | 7 | 10.29 | ||
| AJCC T stage | 0.325 | 0.955 | ||||
| T1 | 7 | 4.19 | 3 | 4.41 | ||
| T2 | 53 | 31.74 | 22 | 32.35 | ||
| T3 | 65 | 38.92 | 24 | 35.29 | ||
| T4 | 42 | 25.15 | 19 | 27.94 | ||
| AJCC N stage | 1.129 | 0.288 | ||||
| N0 | 66 | 39.52 | 32 | 47.06 | ||
| N1 | 101 | 60.48 | 36 | 52.94 | ||
| Surgery | 0.625 | 0.429 | ||||
| No | 152 | 91.02 | 64 | 94.11 | ||
| Yes | 15 | 8.98 | 4 | 5.88 | ||
| Radiotherapy | 0.283 | 0.595 | ||||
| No | 117 | 70.06 | 50 | 73.53 | ||
| Yes | 50 | 29.94 | 18 | 26.47 | ||
| Chemotherapy | 0.157 | 0.692 | ||||
| No | 71 | 42.51 | 27 | 39.71 | ||
| Yes | 96 | 57.49 | 41 | 60.29 | ||
| Tumor size | 2.186 | 0.335 | ||||
| 4-38 mm | 63 | 37.72 | 29 | 42.65 | ||
| 39-67 mm | 74 | 44.31 | 32 | 47.06 | ||
| 68-150 mm | 30 | 17.96 | 7 | 10.29 | ||
| Brain metastasis | 0.079 | 0.779 | ||||
| No | 159 | 95.21 | 66 | 97.06 | ||
| Yes | 8 | 4.79 | 2 | 2.94 | ||
| Liver metastasis | 0.975 | 0.323 | ||||
| No | 55 | 32.93 | 27 | 39.71 | ||
| Yes | 112 | 67.07 | 41 | 60.29 | ||
| Lung metastasis | 0.975 | 0.323 | ||||
| No | 112 | 67.07 | 41 | 60.29 | ||
| Yes | 55 | 32.93 | 27 | 39.71 | ||
*T test.