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. 2021 Dec 13;10(4):e578. doi: 10.1002/iid3.578

Table 1.

Results from the linear mixed‐effects models for estimation of coefficients of variation (CV, %) of biological and analytical variation, including 95% confidence intervals (CIs)

Based on the model for nontransformed tryptase Based on the model for log‐transformed tryptase
Estimate CI, simulated tryptase CI, simulated log tryptase Estimate CI, simulated log tryptase CI, simulated tryptase
Between‐subject CV, % 31.5 18.8–45.4 20.9–50.6 35.2 21.5–49.8 19.5–81.2
Within‐subject CV, % 5.6 4.1–7.4 3.8–7.4 5.4 3.9–6.6 4.3–15.4
Analytical CV, % 6.3 5.2–7.8 5.9–8.2 6.6 5.8–7.4 5.7–17.3
RCV, % 23.5 19.5–28.8 22.0–28.4
RCV, %, down −21.0 −22.9 to −19.2 −47.6 to −19.4
RCV, %, up 26.6 23.8–29.6 24.1–90.7

Abbreviation: RCV, reference change value.