Table 2.
Description of the study participants subdivided by different levels of androgens.
| Control (n = 139) | Normal-androgenic PCOS (n = 35) | Hyperandrogenic PCOS (n = 54) | P a-value | P b-value | |
|---|---|---|---|---|---|
| Age (year) | 31.00 (29.00-33.00) | 32.00 (30.00-33.00) | 31.50 (30.00-33.25) | NS | NS |
| BMI (kg/m2) | 24.00 (22.20-26.30) | 24.97 (22.80-27.34) | 26.30 (23.73-29.01) | NS | NS |
| Leptin (ng/mL) | 9.71 (6.85-14.45) | 14.44 (9.96-15.95) | 15.84 (12.30-20.33) | P < 0.001 | P < 0.05 |
| FPG (mM) | 5.18 (4.98-5.55) | 5.00 (4.82-5.43) | 5.33 (5.05-5.54) | P < 0.05 | P < 0.05 |
| FSI (mIU/L) | 11.00 (8.50-14.90) | 11.50 (8.70-19.10) | 15.80 (11.50-22.80) | NS | P < 0.05 |
| HOMA-IR | 2.54 (1.97-3.58) | 2.56 (1.86-4.09) | 3.81 (2.75-5.30) | NS | P < 0.05 |
| Free testosterone (nmol/L) | 0.023 (0.017-0.030) | 0.022 (0.017-0.032) | 0.038 (0.026-0.044) | NS | P < 0.001 |
| DHEAS (nmol/L) | 3108 (2040-4012) | 3283 (2385-4884) | 4867 (3157-6512) | P < 0.05 | P < 0.05 |
| Total testosterone (ng/mL) | 0.49 (0.36-0.59) | 0.53 (0.43-0.62) | 0.79 (0.70-0.91) | P < 0.05 | P < 0.001 |
| FSH (mIU/L) | 7.08 (5.70-8.27) | 6.09 (5.01-7.42) | 6.44 (5.64-7.74) | P < 0.05 | NS |
| LH (mIU/L) | 3.70 (2.92-5.22) | 9.07 (5.07-12.98) | 11.33 (5.75-15.58) | P < 0.001 | NS |
| LDL-C (mM) | 2.68 ± 0.70 | 3.05 ± 0.79 | 3.08 ± 0.70 | P < 0.05 | NS |
| HDL-C (mM) | 1.22 (1.04-1.41) | 1.11 (0.95-1.40) | 1.10 (0.96-1.35) | NS | NS |
| Prolactin(ng/mL) | 10.40 (8.24-13.47) | 9.54 (7.56-11.57) | 9.33 (7.04-12.44) | NS | NS |
| Progestin (mIU/mL) | 0.54 (0.34-0.75) | 0.49 (0.34-0.70) | 0.66 (0.37-1.01) | NS | NS |
| AMH (ng/mL) | 2.99 (1.43-4.76) | 8.63 (5.98-11.77) | 8.13 (4.81-11.62) | P < 0.001 | NS |
| Estrogen (pg/mL) | 47.00 (36.00-65.00) | 53.00 (35.75-86.00) | 52.50 (41.00-67.00) | NS | NS |
| Total cholesterol (mM) | 4.45 ± 0.80 | 4.84 ± 0.84 | 4.92 ± 0.85 | P < 0.05 | NS |
| Triglycerides (mM) | 1.00 (0.71-1.57) | 1.53 (0.93-1.93) | 1.42 (1.00-2.21) | P < 0.05 | NS |
| TSH (µIU/mL) | 1.82 (1.46-2.57) | 1.83 (1.16-2.33) | 1.69 (1.23-2.21) | NS | NS |
AMH, anti-Müllerian hormone; BMI, body mass index; DHEAS, dehydroepiandrosterone sulfate; FSH, follicle-stimulating hormone; FSI, fasting serum insulin; FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; LDL-C, low-density lipoprotein cholesterol; LH, luteinizing hormone; TSH, thyroid-stimulating hormone; NS, not significant. The Mann-Whitney U test was used for non-normally distributed data, and Student’s t test was used for normally distributed data. aComparing the normal-androgenic PCOS patients and controls after post-hoc test. bComparing normal-androgenic PCOS patients and hyperandrogenic PCOS patients after post-hoc test.