Variance analysis of the regression model.
| Source | Sum of squares | df | Mean square | F value | p-value prob > F | |
|---|---|---|---|---|---|---|
| Model | 7238.41 | 14 | 517.03 | 491.03 | <0.0001 | Significant |
| X 1-temperature | 575.56 | 1 | 575.56 | 546.61 | <0.0001 | |
| X 2-time | 340.66 | 1 | 340.66 | 323.53 | <0.0001 | |
| X 3-substrate ratio | 1357.43 | 1 | 1357.43 | 1289.17 | <0.0001 | |
| X 4-IL dosage | 1755.57 | 1 | 1755.57 | 1667.28 | <0.0001 | |
| X 1 X 2 | 17.31 | 1 | 17.31 | 16.44 | 0.0012 | |
| X 1 X 3 | 23.55 | 1 | 23.55 | 22.36 | 0.0003 | |
| X 1 X 4 | 128.88 | 1 | 128.88 | 122.40 | <0.0001 | |
| X 2 X 3 | 9.84 | 1 | 9.84 | 9.35 | 0.0085 | |
| X 2 X 4 | 35.55 | 1 | 35.55 | 33.76 | <0.0001 | |
| X 3 X 4 | 13.00 | 1 | 13.00 | 12.34 | 0.0034 | |
| X 1 2 | 66.56 | 1 | 66.56 | 63.21 | <0.0001 | |
| X 2 2 | 332.96 | 1 | 332.96 | 316.22 | <0.0001 | |
| X 3 2 | 915.79 | 1 | 915.79 | 869.73 | <0.0001 | |
| X 4 2 | 944.33 | 1 | 944.33 | 896.84 | <0.0001 | |
| Residual | 14.74 | 14 | 1.05 | |||
| Lack of fit | 13.11 | 10 | 1.31 | 3.21 | 0.1364 | Not significant |
| Pure error | 1.64 | 4 | 0.41 | |||
| Cor total | 7253.15 | 28 | ||||
| R 2 | 0.9980 |