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. 2022 Mar 9;9:847259. doi: 10.3389/fcvm.2022.847259

Table 4.

Comparison of procedural and post-procedural outcomes between patients implanted with large borderline-SE vs. non-borderline-BE devices; or large borderline-BE vs. non-borderline-SE devices.

BAAS only for SE device p-value BAAS only for BE device p-value
Large SE-borderline valve (n = 150) BE- non-borderline valve (n = 70) Large BE-borderline valve (n = 102) SE- non-borderline valve (n = 96)
Need for post dilatation 57 (38) 9 (12.8) 0.0001 8 (7.8) 34 (35.4) 2.97e-06
Device success (VARC-2) (%) 146 (97) 70 (100) 0.554 101 (99) 93 (96.8) 0.11
Need for a second valve (%) 2 (1.3) 0 (0) 1 2 (1.9) 2 (2) 1
Valve malposition (%) 2 (1.3) 0 (0) 1 0 (0) 1 (1) 1
Valve migration (%) 1 (0.6) 0 (0) 1 0 (0) 0 (0)
Ischemic stroke/TIA (%) 2 (0.1) 0 (0) 1 0 (0) 2 (2) 0.508
Endocarditis (%) 0 (0) 1 (1.4) 0.36 1 (0.98) 1 (1) 1
Procedural mortality (%) 2 (0.1) 0 (0) 0.528 0 (0) 1 (1.6) 0.927
Coronary obstruction (%) 0 (0) 2 (3.3) 0.166 0 (0) 1 (1.6) 0.927
New LBBB (%) 34 (23) 17 (28.3) 0.615 29 (28) 27 (28.1) 0.737
New pacemaker (%) 17 (11.3) 9 (15) 0.579 21 (20) 17 (17.7) 0.499
AV mean pressure (mmHg) 7.9 ± 5.4 (7, 4) 12.1 ± 4.5 (12, 8) 1.70e-10 9.9 ± 3.7 [9.6, 5] 7.8 ± 3.5 (7, 5) 3.90e-05
PVL per echo+ 0.246 0.191
None (%) 82 (54.6) 47 (67.1) 68 (66.6) 52 (54)
Mild (%) 54 (36) 20 (28.5) 29 (28.4) 36 (37.5)
Mild-mod (%) 11 (7.3) 3 (4.3) 4 (3.9) 6 (6.25)
Moderate (%) 3 (2) 0 (0) 1 (0.98) 2 (2)
Moderate-severe (%) 0 (0) 0 (0) 0 (0) 0 (0)
Overall PVL per echo+ 68 (45.3) 23 (32.8) 0.106 34 (33) 44 (45.8) 0.0818
Large SE-borderline
valve
(n = 93)
BE- non-borderline
valve
(n = 32)
Large BE-borderline
valve
(n = 94)
SE- non-borderline
valve
(n = 39)
PVL per echo+ 0.699 0.0015
None (%) 42 (45.1) 16 (50) 68 (72.3) 14 (35.8)
Mild (%) 40 (45.9) 14 (43.7) 23 (25.8) 20 (51.2)
Mild-moderate (%) 10 (11.4) 2 (6.25) 3 (3.37) 4 (10.2)
Moderate (%) 1 (1.1) 0 (0) 0 (0) 1 (3)
Moderate-severe (%) 0 (0) 0 (0) 0 (0) 0 (0)
Overall PVL per echo+ 51 16 0.413 26 25 0.0003

Values are mean ± SD or [median, interquartile range (IQR)] or n (%). VARC, valve academic research consortium; TIA, transient ischemic attack; LBBB, left bundle branch block; AV, aortic valve; PVL, paravalvular leak; SE, self-expandable; BE, balloon-expandable; THV, transcatheter heart valve; echo, echocardiography.

+

subgroup of patients who did undergo post-dilatation. Post-procedural outcomes (during index hospitalization) were endocarditis and new pacemaker implantation.