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. 2022 Mar 9;9:840689. doi: 10.3389/fcvm.2022.840689

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Copyright © 2022 Chevalier, Selim, Castro, Cuvilly, Baste, Richard, Pareige and Bellien.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic diagram of the experimental procedure. CPB, cardiopulmonary bypass; IR, ischemia-reperfusion; (A) Glycocalyx degradation. Plasma concentration of syndecan-1. (B) Relaxation to acetylcholine after precontraction with phenylephrine (endothelium-dependent relaxation). Responses are expressed as percentage relaxation of phenylephrine-induced precontraction (mean ± SEM).