FIG. 3.

Relationship between bacteriostatic activities of fluoroquinolones against gyrA mutants and gyrA parC mutants. The MIC₉₉s for gyrA (Fig. 2A) and gyrA parC (Fig. 2B) mutants, normalized to the MIC₉₉s of wild-type and parC mutant cells, respectively, as described in the legend for Fig. 2, were plotted such that each data point represents one gyrA allele with wild-type and mutant parC alleles. Symbols: ■, gatifloxacin; □, AM1121; and ○, ciprofloxacin. Arrows indicate values for the D82A gyrA allele.