Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| Value | Mice | Piglets | Paediatric population (Sato et al., 2008) | ||
|---|---|---|---|---|---|
| Tebipenem SQ (n = 3) | Tebipenem PO(n = 3) | Tebipenem-Pivoxil PO(n = 3) | Tebipenem-Pivoxil PO(n = 2) | Tebipenem-Pivoxil PO | |
| Cmax (µg/ml) | 71.0 ± 15.3 | 3.7 ± 0.9 | 61.6 ± 3.9 | 9.0 ± 0.8 | 7.5 ± 3.9 |
| Tmax [Range] (hr) | [0.25 0.25] | [0.5 1] | [0.25 0.5] | [2 2] | 0.7 ± 0.2 |
| AUC0-tlast (hr*µg/mL) | 80.4 ± 7.7 | 7.5 ± 1.5 | 93.8 ± 2.7 | 32.6 ± 3.9 | 16.1 ± 3.3 |
| Bioavailability (%) | 44 ± 4 | 4 ± 1 | 52 ± 1 | ND | ND |
