Table 3.
Changes in clinical, CMR and blood parameters of the 13 patients who underwent the two CMRs at medians of 3 and 11 months from peak troponin respectively.
| 1st CMR | 2nd CMR | P-value | |
|---|---|---|---|
| BMI (kg/m2) | 27.4 [25.4–31.9] | 30.9 [28.8–33.60] | 0.103 |
| Heart rate (bpm) | 77.0 [65.4–82.2] | 64.1 [57.5–79.3] | 0.046 |
| Systolic BP (mmHg) | 134 [125–145] | 142 [127–156] | 0.173 |
| Diastolic BP (mmHg) | 81 [72–85] | 81 [77–90] | 0.166 |
| End-diastolic LV volume | 63 [53–71] | 61 [51–69] | 0.576 |
| (mL/m2) | |||
| LV ejection fraction (%) | 60 [53–65] | 56 [52–62] | 0.388 |
| LV mass (g/m2) | 70 [60–82] | 68 [59–82] | 0.419 |
| LV mass/volume ratio | 1.23 [1.06–1.26] | 1.12 [1.02–1.34] | 0.650 |
| End-diastolic RV volume | 63 [53–71] | 61 [51–69] | 0.576 |
| (mL/m2) | |||
| RV ejection fraction (%) | 60 [53–65] | 56 [52–62] | 0.388 |
| Myocardial T1 (ms) | 1,257 [1,225–12,646] | 1,233 [1,192–1,256] | 0.038 |
| Myocardial T2 (ms) | 37.6 [35.9–39.5] | 38.0 [36.5–40.5] | 0.576 |
| Myocardial ECV (%) | 27.4 [25.7–31.1] | 25.9 [23.1–27.3] | 0.007 |
| Delayed retention | 2 (14%) | 2 (14%) | 1.000 |
| myocarditis pattern | |||
| Skeletal T1 (ms) | 1,122 [1,104–1,173] | 1,134 [1,104–1,228] | 0.382 |
| Skeletal ECV (%) | 15.6 [14.2–19.2] | 12.7 [12.2–14.9] | 0.001 |
| Hematocrit (%) | 42.2 [40.1–43.4] | 42.4 [39.2–44.5] | 1.000 |
| C Reactive Protein (mg/mL) | 4 (4) | 4 [4–9.3] | 0.028 |
| Troponin Ic (ng/ml) | 5.5 [2.0–13.2] | 5.0 [2.75–12.25] | 0.893 |
| Nt-pro BNP (pg/mL) | 111 [41–133] | 56 [35–52] | 0.285 |
| Albumin (g/L) | 42.0 [40.3–47.4] | 44.1 [42.7–46.0] | 0.388 |
| eGFR (ml/min/1.73 m2) | 90 [87–90] | 90 [82–90] | 0.221 |
BMI, body mass index; BNP, brain natriuretic peptide; BP, blood pressure; ECV, extracellular volume; eGFR, glomerular filtration rate estimated with the CKD-EPI formula and truncated at 90 ml/min/1.73 m2; LV, left ventricle; RV, right ventricle; T1, longitudinal relaxation time; T2, transversal relaxation time.