TABLE 8.
The signals of ADRs (4 methods, TOP10 and off-label).
Drug | ADR | ROR (LI95) | PRR | PRR (LI95) | χ2 | IC(LI95) |
---|---|---|---|---|---|---|
perphenazine | Tongue induration | 4.34 | 15.51 | 4.36 | 21.05 | 2.23 |
sulpiride | Insomnia | 5.70 | 13.29 | 5.60 | 45.33 | 2.34 |
chlorpromazine | Blood pressure decreased | 3.55 | 11.81 | 3.58 | 17.01 | 2.07 |
chlorpromazine | Orthostatic hypotension | 4.79 | 10.63 | 4.70 | 37.87 | 2.17 |
chlorpromazine | Pruritus | 3.38 | 11.19 | 3.41 | 16.04 | 2.01 |
haloperidol | Dystonia | 6.66 | 9.54 | 6.14 | 136.25 | 2.05 |
olanzapine | Obesity | 2.13 | 8.48 | 2.13 | 9.36 | 0.78 |
amisulpride | Pollakiuriaa | 2.00 | 7.95 | 2.00 | 7.74 | 1.03 |
chlorpromazine | Rash | 2.74 | 7.46 | 2.76 | 14.91 | 1.62 |
haloperidol | Nuchal rigidity | 2.57 | 7.32 | 2.57 | 14.50 | 1.21 |
ziprasidone | Dyspnoeaa | 1.64 | 5.07 | 1.65 | 7.27 | 0.77 |
quetiapine | Urinary incontinencea | 1.41 | 5.28 | 1.41 | 4.62 | 0.65 |
olanzapine | Hepatic function abnormala | 2.17 | 3.18 | 2.12 | 33.54 | 0.80 |
The superscript a represents off-label adverse reactions.