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. 2022 Mar 9;13:843368. doi: 10.3389/fphar.2022.843368

TABLE 5.

Serum thyroid hormone levels of SD rats treated with sodium p-hydroxybenzoate for 90 days.

sodium p-hydroxybenzoate (mg/kg)
0 125 250 500
NO. of animals examined 10 10 10 10
Males
 T3 (ng/ml) 1.14 ± 0.26 1.08 ± 0.23 1.11 ± 0.15 1.10 ± 0.17
 T4 (ng/ml) 41.47 ± 3.81 40.78 ± 2.56 42.16 ± 2.82 41.88 ± 2.19
 TSH (ng/ml) 4.12 ± 0.24 4.20 ± 0.19 4.16 ± 0.20 4.08 ± 0.24
Females
 T3 (ng/ml) 1.25 ± 0.27 1.27 ± 0.15 1.17 ± 0.13 1.24 ± 0.18
 T4 (ng/ml) 28.66 ± 3.66 29.59 ± 3.18 27.64 ± 2.26 28.45 ± 2.88
 TSH (ng/ml) 2.37 ± 0.19 2.29 ± 0.12 2.20 ± 0.12 2.19 ± 0.14

T3, triiodothyronine; T4, thyroxine; TSH, thyroid-stimulating hormone.

Data are expressed as means ± SD. *p < 0.05, (significantly different from the control group).

One-way ANOVA test and Bonferroni test.