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. 2022 Mar 9;13:843368. doi: 10.3389/fphar.2022.843368

TABLE 7.

Urinalysis values of male and female SD rats treated with sodium p-hydroxybenzoate for 90 days.

Urinalysis parameters severity scale sodium p-hydroxybenzoate (mg/kg)
Male Female
0 125 250 500 0 125 250 500
Protein
7/10 6/10 6/10 5/10 6/10 7/10 6/10 6/10
1+ 2/10 2/10 2/10 3/10 2/10 2/10 2/10 2/10
2+ 1/10 2/10 2/10 2/10 2/10 1/10 2/10 2/10
3+ 0/10 0/10 0/10 0/10 0/10 0/10 0/10 0/10
Ketones
10/10 10/10 10/10 10/10 10/10 10/10 10/10 10/10
Glucose
10/10 10/10 10/10 10/10 10/10 10/10 10/10 10/10
Occult blood
10/10 10/10 10/10 10/10 10/10 10/10 10/10 10/10
Urobilinogen
+/− 10/10 10/10 10/10 10/10 10/10 10/10 10/10 10/10
Bilirubin
8/10 8/10 8/10 8/10 9/10 9/10 8/10 8/10
1+ 2/10 2/10 2/10 2/10 1/10 1/10 2/10 2/10
Urinary sediments
Red blood cell 10/10 10/10 10/10 10/10 10/10 10/10 10/10 10/10
White blood cell 10/10 10/10 10/10 10/10 10/10 10/10 10/10 10/10
Cast 10/10 10/10 10/10 10/10 10/10 10/10 10/10 10/10

No significant differences were noted in any treated groups from control group.

Protein) −: 0 g/L, 1+: 0.3 g/L, 2+: 1.0 g/L, 3+: ≥3.0 g/L.

Ketones) −: 0 mmol/L.

Glucose) −: 0 mmol/L.

Occult blood) −: 0 cells.

Bilirubin) −: 0 μmol/L, 1+: 8.6 μmol/L.