Table 3.
Multivariable logistic regression model for ECMO support in patients with ARDS.
| Variable | OR (95% CI) | P-value |
|---|---|---|
| Age, year | 0.95 (0.95, 0.96) | < 0.001 |
| Sex, male (vs female) | 0.98 (0.82, 1.17) | 0.805 |
| Annual Income level at ARDS treatment | ||
| Q2 (vs Q1; Lowest) | 1.42 (1.09, 1.85) | 0.010 |
| Q3 (vs Q1; Lowest) | 1.37 (1.07, 1.77) | 0.014 |
| Q4 (Highest) (vs Q1; Lowest) | 1.35 (1.06, 1.70) | 0.013 |
| Unknown (vs Q1; Lowest) | 1.12 (0.55, 2.32) | 0.752 |
| Admitting department: IM (vs non-IM) | 0.40 (0.33, 0.49) | < 0.001 |
| Hospital admission | ||
| Transfer from other hospital | 1 | |
| Admission through Emergency Room | 1.13 (0.73, 1.73) | 0.587 |
| Admission through outpatient clinic | 1.36 (0.86, 2.14) | 0.187 |
| Annual case volume of ARDS admission | ||
| Q2: 5–14 (vs Q1 ≤ 4) | 6.97 (3.84, 12.63) | < 0.001 |
| Q3: 15–28 (vs Q1 ≤ 4) | 5.24 (2.90, 9.49) | < 0.001 |
| Q4 ≥ 28 (vs Q1 ≤ 4) | 6.50 (3.60, 11.72) | < 0.001 |
| Main diagnosis of ARDS (vs secondary diagnosis of ARDS) | 1.32 (1.11, 1.58) | 0.002 |
| Sepsis associated ARDS | 1.63 (1.32, 2.01) | < 0.001 |
| Diagnosis of shock during hospitalization | 1.50 (1.16, 1.93) | 0.002 |
| CCI at hospital admission for ARDS | ||
| 2–3 (n = 2,722) vs 0–1 (n = 1,463) | 1.43 (1.08, 1.88) | 0.011 |
| 4–5 (n = 2,526) vs 0–1 (n = 1,463) | 1.20 (0.89, 1.60) | 0.227 |
| 6–7 (n = 1,767) vs 0–1 (n = 1,463) | 1.07 (0.77, 1.49) | 0.675 |
| ≥ 8 (n = 1,697) vs 0–1 (n = 1,463) | 0.89 (0.63, 1.25) | 0.504 |
| NMBA use | 7.39 (5.83, 9.37) | < 0.001 |
| Duration of CRRT use, day | 1.13 (1.09, 1.16) | < 0.001 |
| Duration of Mechanical Ventilator use, day | 1.03 (1.02, 1.04) | < 0.001 |
| Experience of CPR during hospitalization | 1.70 (1.36, 2.13) | < 0.001 |
| Year of admission for ARDS | ||
| 2015 (vs 2014) | 1.13 (0.81, 1.58) | 0.464 |
| 2016 (vs 2014) | 1.05 (0.76, 1.44) | 0.770 |
| 2017 (vs 2014) | 1.12 (0.81, 1.56) | 0.483 |
| 2018 (vs 2014) | 1.30 (0.94, 1.78) | 0.110 |
| 2019 (vs 2014) | 1.57 (1.14, 2.15) | 0.005 |
Hosmer Lemeshow test: Chi-square, 3.66, df = 8, P = 0.886.
ARDS acute respiratory distress syndrome, ECMO extracorporeal membrane oxygenation, OR odds ratio, CI confidence interval, IM internal medicine, USD United States Dollars, NMB neuromusclar blockade, CRRT continuous renal replacement therapy, CPR cardiopulmonary resuscitation.