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. 2022 Mar 9;12:845540. doi: 10.3389/fonc.2022.845540

Figure 3.

Figure 3

Association between infection and post CD19-CAR T cell therapy immune mediated side effects. The proportion of patients experiencing at least one infection in the early post CAR T cell therapy period (day 1 to day 28), displayed by infection category and severity of CAR T cell therapy related immune mediated side effects (CRS, cytokine release syndrome; NTX, neurotoxicity; carHLH, CAR-associated hemophagocytic lymphohistiocytosis). Patients with at least 1 infection in a given category (B, bacterial; V, viral; F, fungal) are presented in the colored bars, with a patient contributing up to one infection per category. Patients not having an infection in the given category are accounted for in the gray bar. Distribution is by patients by highest grade (A) CRS and (B) neurotoxicity, or presence/absence of (C) carHLH.