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. 2022 Mar 7;9:833995. doi: 10.3389/fmed.2022.833995

Table 2.

Difference between demographic and clinical variables in SLE patients with and without DED.

Parameters DED patients in SLE (n = 33) Non- DED patients in SLE (n = 63) P
Alcohol use, n(%) 2 (6.1%) 2 (3.2%) 0.893
Tobacco use, n(%) 1 (3.0%) 2 (3.2%) 0.969
Corticosteriods use, n(%) 24 (72.7%) 43 (68.3%) 0.650
Hydroxychloroquine use, n(%) 20 (60.6%) 33 (52.4%) 0.441
Hypertension 3 (9.1%) 4 (6.3%) 0.624
Diabetes 3 (9.1%) 3 (4.8%) 0.698
CRP, mg/L 0.70 (0.20,1.35) 0.60 (0.20,2.10) 0.978
C3,g/L 0.86 (0.68,1.02) 0.78 (0.64,0.92) 0.151
ESR, mm/h 19.0 (13.5,34.5) 20.0 (11.0,33.0) 0.746
SLEDAI 7.0 (5.0,13.5) 4.0 (2.0,8.5) <0.05
Age 42.1 ± 11.2 33.2 ± 10.5 <0.05

Data is presented as mean ± SD, median and interquartile range (IQR, 25–75%), or number of participants (% of participants). SLE, Systemic Lupus Erythematosus; CRP, C-Reactive Protein; C3, complement levels; ESR, Erythrocyte Sedimentation Rate; SLEDAI, Systemic Lupus Erythematosus Disease Activity Index. The bold values means significant results.