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. 2022 Mar 7;9:833995. doi: 10.3389/fmed.2022.833995

Table 3.

Diagnosis efficiency of SLEAI, Age, NIKBUT and combo parameters for DED by ROC analysis.

Parameters Cut-off Area under curve Sensitivity/% Specificity/% Youden's index
SLEDAI 4.5 0.752 87.9% 60.3% 0.482
Age 33.5 0.748 81.8% 61.9% 0.437
NIKBUT 9.415 0.896 76.2% 97.0% 0.732
SLEDAI+Age 0.791 87.9% 61.9% 0.498
SLEDAI+NIKBUT 0.910 97.0% 73.0% 0.700
Age+NIKBUT 0.909 97.0% 76.2% 0.732
SLEDAI+Age+NIKBUT 0.915 75.8% 92.1% 0.678

SLEDAI, Systemic Lupus Erythematosus Disease Activity Index; NIKBUT, Non-Invasive Tear Film Breakup Time.