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. 2022 Mar 9;9:774224. doi: 10.3389/fmed.2022.774224

Table 3.

The DALYs of infective endocarditis in 1990/2019 and temporal trends.

Characteristics 1990 2019 1990–2019
DALYs No × 103 (95% CI) Age standardized DALYs/105 No. (95% CI) DALYs No × 103 (95% CI) Age standardized DALYs/105 No. (95% CI) EAPC No. (95% CI)
Overall 1,118.12 (836.79~1,318.66) 22.78 (17.98~26.97) 1,723.59 (1,355.67~1,935.25) 21.93 (17.17~24.6) −0.21 (−0.35~-0.08)
Sex
Male 617.35 (463.03~749.04) 25.41 (20.09~31.37) 972.61 (735.86~1,123.53) 25.46 (19.06~29.12) −0.05 (−0.18~0.07)
Female 500.77 (319.04~627.69) 20 (13.53~25.53) 750.98 (536.88~870.75) 18.33 (13.23~21.33) −0.41 (−0.56~−0.25)
Socio-demographic factor
High SDI 157.8 (131.72~234.56) 16.27 (13.51~24) 386.32 (212.21~461.4) 22.33 (12.61~26.23) 1.32 (0.95~1.7)
High-middle SDI 213.6 (170.09~253.17) 19.46 (15.45~23.03) 325.01 (238.95~365.72) 18.38 (13.65~20.7) −0.42 (−0.62~−0.23)
Middle SDI 379.69 (280.63~449.48) 24.34 (19.13~28.65) 454.53 (390.82~582.66) 18.55 (15.94~23.45) −1.2 (−1.34~−1.07)
Low-middle SDI 212.42 (138.86~271.28) 21.77 (16.16~25.98) 325.38 (262.88~395.76) 20.48 (16.51~24.91) −0.32 (−0.39~−0.25)
Low SDI 153.84 (79.37~223.34) 31.18 (19.43~43.54) 230.95 (173.53~299.55) 25.3 (18.62~32.83) −0.82 (−0.92~−0.72)
Region
East Asia 225.16 (123.24~291.15) 0.48 (0.31~0.58) 127.6 (100.95~153.97) 0.29 (0.21~0.34) −4.4 (−4.91~−3.88)
Southeast Asia 151.03 (122.05~217.56) 1.22 (0.97~1.69) 255.83 (208.03~359.59) 1.29 (1.04~1.76) −0.26 (−0.46~−0.06)
Oceania 1.55 (1.03~2.38) 1.25 (0.78~2.25) 4.61 (3.1~6.41) 1.64 (1.13~2.26) 1.26 (1.13~1.4)
Central Asia 3.77 (3.06~4.52) 0.21 (0.16~0.27) 8.27 (6.95~11.3) 0.33 (0.28~0.44) 1.35 (1.05~1.65)
Central Europe 14.36 (12.75~20.56) 0.34 (0.3~0.5) 23.26 (13.6~29.04) 0.48 (0.28~0.59) 1.16 (0.94~1.38)
Eastern Europe 35.68 (27.36~65.37) 0.39 (0.3~0.7) 79.48 (53.86~97.14) 0.78 (0.56~0.95) 2.81 (2.35~3.27)
High-income Asia Pacific 33.18 (22.99~38.31) 0.79 (0.53~0.92) 56.07 (30.42~69.53) 0.75 (0.36~0.97) −1.72 (−1.99~−1.44)
Australasia 2.93 (2.53~4.18) 0.54 (0.46~0.79) 7.44 (3.85~9.11) 0.82 (0.39~1.04) 1.05 (0.8~1.3)
Western Europe 77.71 (61.59~135.36) 0.72 (0.56~1.3) 193.13 (100.18~232.92) 1.28 (0.63~1.57) 1.91 (1.51~2.32)
Southern Latin America 14.77 (11.08~19.2) 1.38 (0.94~1.77) 31.78 (25.79~39.14) 1.84 (1.42~2.16) 0.58 (0.34~0.83)
High-income North America 49.8 (40.43~82.72) 0.61 (0.46~1.08) 159.45 (85.9~187.88) 1.36 (0.68~1.65) 2.66 (2.01~3.32)
Caribbean 9.71 (7.34~14.09) 0.75 (0.65~0.97) 15.38 (11.98~19.67) 0.88 (0.71~1.08) 0.54 (0.47~0.61)
Andean Latin America 11.56 (7.57~15.8) 0.8 (0.59~0.94) 11.27 (8.61~14.62) 0.59 (0.44~0.76) −1.8 (−1.88~−1.72)
Central Latin America 20.35 (17.53~27.1) 0.4 (0.35~0.58) 42.52 (29.45~52.97) 0.54 (0.38~0.67) 0.9 (0.68~1.12)
Tropical Latin America 43.84 (35.45~65.78) 0.82 (0.7~1.35) 79.11 (61.28~94.86) 1.06 (0.74~1.19) 0.29 (0.08~0.5)
North Africa and Middle East 82.57 (45.09~114.67) 0.83 (0.64~0.99) 91.25 (65.94~111.62) 0.65 (0.51~0.79) −1.43 (−1.49~−1.36)
South Asia 150.64 (111.05~200.69) 0.64 (0.51~0.79) 287.1 (225.89~360.89) 0.64 (0.51~0.8) −0.15 (−0.21~−0.09)
Central Sub-Saharan Africa 14.47 (7.6~22.28) 1.17 (0.58~2.03) 23.75 (14.08~36.48) 1.02 (0.56~1.68) −0.83 (−0.89~−0.77)
Eastern Sub-Saharan Africa 54.04 (28.51~79.44) 1.14 (0.55~2.05) 77.69 (48.46~117.8) 0.91 (0.5~1.49) −1.2 (−1.3~−1.1)
Southern Sub-Saharan Africa 17.38 (11.47~20.9) 1.01 (0.7~1.2) 18.77 (15.33~23.82) 0.79 (0.65~1) −1.69 (−2.15~−1.23)
Western Sub-Saharan Africa 103.62 (44.84~152.58) 1.2 (0.73~1.76) 129.82 (95.04~177.18) 0.78 (0.61~1.02) −1.89 (−2.12~−1.66)

DALY, disability-adjusted life-years; SDI, social-demographic index; EAPC, estimated annual percentage change.