Table 1.
Species | SCI models | Source | Transplant route | Transplant dose | WMD | I 2 |
---|---|---|---|---|---|---|
SD rats (27) | Contusion (23) | BMSCs-Exo (21) | Tail veins (19) | 100 μg (8) | 1 week: 1.47 [0.30, 2.65] 2 weeks: 2.26 [1.04, 3.49] 3 weeks: 2.48 [0.27, 4.70] 4 weeks: 3.72 [1.81, 5.63] |
24.0% 20.5% 26.6% 25.4% |
SD rats (27) | Contusion (23) | BMSCs-Exo (21) | Tail veins (19) | 200 μg (11) | 1 week: 1.76 [1.16, 2.36] 2 weeks: 2.98 [2.33, 3.63] 3 weeks: 3.74 [2.93, 4.56] 4 weeks: 4.36 [3.46, 5.26] |
16.9% 18.3% 15.5% 13.9% |
SD rats (27) | Contusion (23) | BMSCs-Exo (21) | Subcutaneous (1) | |||
SD rats (27) | Contusion (23) | BMSCs-Exo (21) | Not reported (1) | |||
SD rats (27) | Contusion (23) | NSCs-Exo (2) | Tail veins (2) | 20 μg (1) | ||
SD rats (27) | Contusion (23) | NSCs-Exo (2) | Tail veins (2) | Not reported (1) | ||
SD rats (27) | Transection (3) | BMSCs-Exo (2) | Intranasal (1) | |||
SD rats (27) | Transection (3) | BMSCs-Exo (2) | Tail veins (1) | |||
SD rats (27) | Transection (3) | HpMSC-Exo (1) | ||||
SD rats (27) | Not reported (1) | |||||
C57BL/6 mice (3) | Not reported (3) | |||||
Wistar rats (2) | Hemi-sectioned (1) | |||||
Wistar rats (2) | Contusion (1) |