Table 1.
Sources and binding scores (in kcal/mol) of selected AMPs docked against selected receptor proteins of deadly pathogenic bacterial species.
| Sr. no. | AMP | Source | A. baumannii | M. tuberculosis | H. pylori | MRSA | S. enterica |
|---|---|---|---|---|---|---|---|
| 1 | Napin | Brassica napus | −158.7 ± 12.2 | −107.8 ± 14.3 | −86.2 ± 4.9 | −99.1 ± 9.1 | −84.2 ± 9.1 |
| 2 | Snakin-1 | Solanum tuberosum | −101.3 ± 8.6 | −54.6 ± 6.1 | −105.0 ± 9.2 | −103.8 ± 6.2 | −75.2 ± 4.3 |
| 3 | Knot1 domain-containing protein | Vitis vinifera | −72.7 ± 8.8 | −52.0 ± 18.1 | −83.1 ± 18.4 | −89.8 ± 5.8 | −83.6 ± 12.3 |
| 4 | Amaranthus caudatus-AMP2 | Amaranthus caudatus | −56.6 ± 10.2 | −87.0 ± 7.5 | −55.2 ± 12.2 | −74.0 ± 18.4 | −79.0 ± 8.9 |
| 5 | Antimicrobial peptide EcAMP1 | Echinochloa crus-galli | −124.9 ± 14.0 | −44.0 ± 8.5 | −98.2 ± 9.6 | −98.5 ± 7.0 | −79.1 ± 6.8 |
| 6 | Nigellin-1.1 | Nigella sativa | −68.8 ± 12.9 | −72.2 ± 11.0 | −92.8 ± 4.1 | −65.9 ± 9.0 | −79.0 ± 3.4 |
| 7 | Plant defensin NsD7 | Nicotiana suaveolens x Nicotiana tabacum | −96.8 ± 9.3 | −75.5 ± 10.5 | −80.2 ± 15.0 | −102.8 ± 19.2 | −63.5 ± 12.5 |
| 8 | Flower-specific gamma-thionin | Zea mays | −53.4 ± 10.0 | −39.8 ± 21.8 | −93.5 ± 14.3 | −97.3 ± 24.0 | −81.9 ± 10.1 |
| 9 | Acyclotide ribe 31 | Rinorea bengalensis | −52.9 ± 10.6 | −75.3 ± 4.7 | −50.4 ± 1.5 | −78.2 ± 2.0 | −71.5 ± 18.1 |
| 10 | Antimicrobial peptide 1a | Triticum kiharae | −58.7 ± 1.6 | −70.2 ± 16.9 | −92.8 ± 30.8 | −75.7 ± 7.9 | −64.4 ± 4.3 |