TABLE 2.

Concordance between genotypic and phenotypic drug resistance.

Gene	Antibiotic	Mutation	Kappa Coefficiency (95%CI)
		Thr82Ile	0.2937 [0.0933 – 0.4940]
		Leu406Ile	0.3491 [0.1654 – 0.5328]
gyrA	Moxifloxacin	Asp468Asn	0.3215 [0.1444 – 0.4985]
		Met299Val	0.0034 [−0.0035 – 0.0104]
		Met324Ile	−0.0215 [−0.0637 – 0.0208]
		Thr82Ile	0.0257 [−0.0721 – 0.1236]
		Leu406Ile	0.0773 [−0.0252 – 0.1798]
gyrA	Ciprofloxacin	Asp468Asn	0.0707 [−0.0236 – 0.1650]
		Met299Val	0.0005 [−0.0007 – 0.0016]
		Met324Ile	0.0215 [−0.0639 – 0.0209]
		Ser366Ala	−0.0305 [−0.0919 – 0.0309]
		Gln160His	0.0034 [−0.0035 – 0.0104]
gyrB	Moxifloxacin	Ser416Ala	0.0034 [−0.0035 – 0.0104]
		Val130Ile	−0.0370 [−0.0978 – 0.0237]
		Arg488Met	0.0034 [−0.0035 – 0.0104]
		Ile139Arg	−0.0182 [−0.0608 – 0.0244]
		Ser366Ala	−0.0202 [−0.0626 – 0.0221]
		Gln160His	0.0005 [−0.0007 – 0.0016]
gyrB	Ciprofloxacin	Ser416Ala	0.0005 [−0.0007 – 0.0016]
		Val130Ile	−0.0208 [−0.0631 – 0.0216]
		Arg488Met	0.0005 [−0.0007 – 0.0016]
		Ile139Arg	0.0009 [−0.0009 – 0.0028]
		Arg505Lys	0.4764 [0.2961 – 0.6567]
		Ile548Met	0.4764 [0.2961 – 0.6567]
rpoB	Rifampicin	Asp1232Glu	0.4592 [0.2908 – 0.6670]
		Ile750Met	0.0544 [−0.1297 – 0.0209]
		Asp1160Glu	−0.01 [−0.0549 – 0.0348]
		Ile750Val	−0.0377 [−0.0986 – 0.0232]
		Ile833Leu	0.4789 [0.2908 – 0.6670]
rpoC	Rifampicin	Asn564Lys	0.0058 [−0.0058 – 0.0174]
		Thr543Ile	−0.0214 [−0.0636 – 0.0207]
fusA	Fusidic Acid	Glu117Lys	0.7176 [0.5245 – 0.9107]
pbp2	Meropenem	Ala555Thr	0.1039 [−0.0991 – 0.3068]
pbo3	Meropenem	Tyr721Cys	−0.0214 [−0.0634 – 0.0206]