Table 2.
Colonization efficiency of germ cells from infant boys with cryptorchidism.
| Recipient | Testis | Patient ID | No. human germ cells prepareda | % human cells injected to recipienta | No. human germ cells actually injectedc | No. human germ cell colonies found after transplantationb | No. human germ cells found after transplantationb | % mean colonization efficiencyc |
|---|---|---|---|---|---|---|---|---|
| 1 | left | #1 | 56798 | 5 - 15 | 2840 - 8520 | 43 | 256 | 1.1 |
| right | 5 - 15 | 2840 - 8520 | 51 | 303 | ||||
| 2 | left | #2 | 43097 | 5 - 15 | 2155 - 6465 | 21 | 128 | 0.6 |
| right | 5 - 15 | 2155 - 6465 | 16 | 96 | ||||
| 3 | left | #3 | 10703 | 10 - 20 | 1070 - 2141 | 19 | 112 | 6.3 |
| right | 5 - 15 | 535 - 1605 | 90 | 542 | ||||
| 4 | left | #4 | 3681 | 15 - 25 | 552 - 920 | 19 | 112 | 3.8 |
| right | 25 - 35 | 920 - 1288 | 51 | 303 | ||||
| 5 | left | #5 | 6128 | 20 -30 | 1226 - 1838 | 85 | 511 | 9.0 |
| right | 5 - 15 | 306 - 919 | 56 | 335 | ||||
| 6 | left | #6 | 19841 | 5 - 15 | 992 - 2976 | 77 | 463 | 3.0 |
| right | 19841 | 100 | 19841 | 149 | 894 | |||
| 7 | left | #7 | 11303 | 10 - 20 | 1130 - 2261 | 85 | 693 | 3.1 |
| right | 60 - 70 | 6782 - 7912 | 37 | 187 | ||||
| 8 | left | #8 | 3025 | 5 - 15 | 151 - 454 | 75 | 702 | 18.6 |
| right | 30 - 40 | 908 - 1210 | 43 | 427 | ||||
| 9 | left (7 weeks) | #9 | 14696 | 5 - 15 | 735 - 2204 | 10 | 96 | 0.5 |
| right (7weeks) | 5 - 15 | 735 - 2204 | 0 | 0 | ||||
| 10 | left (6 weeks) | #10 | 7959 | 30 - 40 | 2388 - 3184 | 98 | 1127 | 1.8 |
| right (6 weeks) | 100 | 7959 | 1 | 10 | ||||
| 11 | left (9 weeks) | #11 | 5361 | 60 - 70 | 3217 - 3753 | 86 | 942 | 6.4 |
| right (9 weeks) | 10 - 20 | 536 - 1072 | 74 | 817 |
Recipient testis no. 1 to no. 8 were harvested 8 weeks after xenotransplantation; no.9 to no.11 were harvested 7, 6, 9 weeks after xenotransplantation.
aestimated number; bcounted number; ccalculated number.
No. human germ cells actually injected = No. human germ cells prepared * % human cells actually injected to recipient; Mean colonization efficiency % = (No. human germ cell colonies obtained after transplantation/No. human germ cells actually injected) * 100.