TABLE 6.
Significant pathways for the top 50 hub genes from the PPI network of the host genes of the DE circRNAs.
| Pathway ID | Pathway description | No. of genes | p-value |
|---|---|---|---|
| hsa04512 | ECM-receptor interaction | 14 | 0.0000 |
| hsa05146 | Amoebiasis | 10 | 0.0017 |
| hsa04510 | Focal adhesion | 12 | 0.0031 |
| hsa04151 | PI3K-Akt signaling pathway | 14 | 0.0062 |
| hsa04974 | Protein digestion and absorption | 8 | 0.0091 |
| hsa05145 | Toxoplasmosis | 8 | 0.0166 |
| hsa04110 | Cell cycle | 8 | 0.0228 |
| hsa05162 | Measles | 8 | 0.0273 |
| hsa05160 | Hepatitis C | 8 | 0.0273 |
| hsa00010 | Glycolysis/Gluconeogenesis | 6 | 0.0429 |
| hsa01230 | Biosynthesis of amino acids | 6 | 0.0489 |