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. 2022 Mar 29;25(10):1171–1173. doi: 10.1177/2472555220934421

Figure 1.

Figure 1.

Overall 3D structure of the supercomplex (ACE2-B0AT1)2. The structure (PDB: 6M18) is represented in closed conformation as a ribbon.8 The superstructure is composed of two heterodimers of ACE2-B0AT1; each heterodimer comprises one ACE2 subunit (cyan) and one B0AT1 subunit (blue). In red are shown residues predicted to form the nimesulide binding site on the B0AT1 subunit.