Table 3.
Settings for cause-specific hazards data generation
| Setting 1 | Setting 2 | Setting 3 | Setting 4 | |
|---|---|---|---|---|
| Z associated with AF | Yes | Yes | Yes | No |
| Z associated with death | No | Yes | No | Yes |
| Proportional CSHs | No | No | Yes | Yes |
| CSHR for atrial fibrillation | 0.006*t1.9 | .059*t | 0.5 | 1.0 |
| CSHR for death | 1.0 | .043*t | 1.0 | 0.5 |
| Weibull distribution of CSH | c | |||
| CSH of AF, Z=0 | W(1.2, 39.5) | W(2, 50) | W(2, 35) | W(2, 35) |
| CSH of AF, Z=1 | W(3.1, 29.5) | W(3, 40) | W(2, 49.5) | W(2, 35) |
| CSH of death, Z=0 | W(1.4, 23.4) | W(2, 60) | W(1.4, 30) | W(1.4, 30) |
| CSH of death, Z=1 | W(1.4, 23.4) | W(3, 50) | W(1.4, 30) | W(1.4, 49.22) |
| Lifetime risk, Z=1 | 0.34 | 0.52 | 0.23 | 0.33 |
| Lifetime risk, Z=0 | 0.34 | 0.39 | 0.38 | 0.38 |
| Difference in lifetime risk | 0.00 | 0.12 | −0.15 | −0.05 |
AF: atrial fibrillation, CSH: cause-specific hazard function. CSHR: cause-specific hazard ratio, W: Weibull. Sample size before left truncation was set to n=500 and n=1,000. Right censoring was generated from a Uniform(c,d) distribution, where parameters c and d were set to obtain 25% and 75% probability of censoring at τ. Left truncation times were generated from a Uniform(0,5) distribution for 50% and 80% of individuals.