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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Breast Cancer Res Treat. 2022 Mar 14;192(3):639–648. doi: 10.1007/s10549-022-06509-3

Figure 1: TP53 Gene Structure and Mutation Frequency.

Figure 1:

(a). A diagram of the intron/exon structure of TP53 is drawn to scale. A green arrow denotes the exon containing the start codon and a red arrow denotes the exon containing the stop codon.(b). The frequency of somatic TP53 mutations by codon is plotted. Exons 5 through 8 are denoted by a red line. Intronic mutations affecting splicing are not included. The figure was created in GraphPad Prism 8.