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. Author manuscript; available in PMC: 2023 Apr 1.
Published in final edited form as: Breast Cancer Res Treat. 2022 Mar 14;192(3):639–648. doi: 10.1007/s10549-022-06509-3

Figure 2: Association of age of breast cancer diagnosis with TP53 mutation characteristics.

Figure 2:

The frequency of age of breast cancer diagnosis of all individuals included in the study was plotted by histogram (a). Age of diagnosis was not significantly associated with TP53 GOF versus LOF, p-value =0.5 (b) or dominant negative effect, p-value 0.49 (c). Individuals with a TP53 mutation at a CpG hotspot were slightly, but not significantly younger at age of diagnosis (53.6 years versus 55.0 years), p-value 0.065 (d). P-values were calculated using a Welch two sample T-test. P-values < 0.05 were considered significant. The figure was created in R.